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Buprenorphine's system of action is that is a partial agonist for the mu-opioid receptor and an antagonist for the kappa-opioid receptor.If you take Suboxone or buprenorphine/naloxone or use other opioids, speak with your Health care service provider or pharmacist about receiving Narcan nasal spray.Suboxone is a mix of two medications, buprenorphin

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